Skin substitutes in dermatology

Cultured skin substitutes: a review.

Skin substitutes composed of cultured cells and biopolymers provide alternative materials for study of skin biology and pathology, treatment of skin wounds, safety testing of consumer products, and therapeutic delivery of gene products. Most frequently, substitutes for epidermis consist of cultured keratinocytes and dermal substitutes consist of resorbable biopolymers populated with cultured fi...

Clinical applications of skin substitutes.

A unique understanding of the components of mammalian skin has led to the development of numerous skin substitutes. These skin substitutes attempt to compensate for functional and physiologic deficits present in damaged tissue. Skin substitutes, when appropriately applied in optimized settings, offer a promising solution to difficult wound management. The body of literature on skin substitutes ...

The Aging Skin: Geriatric Dermatology

SUPERFICIAL NECROLYTIC DERMATITIS Superficial necrolytic dermatitis (a.k.a. hepatocutaneous syndrome, metabolic epidermal necrolysis, necrolytic migratory erythema) is a rare disease in dogs and very rare in cats. The disease primarily affects old dogs, with the average age being 10.7 years. Small breeds seem to be over-represented. Clinical signs are most commonly associated with liver disease...

Stereoscopic Skin Mapping for Dermatology

Fitzpatrick skin typing: applications in dermatology.

Fitzpatrick skin phototypes were developed by Thomas B. Fitzpatrick in 1975 based on a person’s skin color and responses to sun exposure in terms of degree of burning and tanning. Though subjective, Fitzpatrick skin typing has a proven diagnostic and therapeutic value. It has been most commonly used to analyze the sun sensitivity in population-based and case-control studies related to cause of ...